{"id":18726,"date":"2025-09-16T10:34:43","date_gmt":"2025-09-16T14:34:43","guid":{"rendered":"https:\/\/valuecare.wpgamma.com\/?p=18726"},"modified":"2025-09-16T10:34:43","modified_gmt":"2025-09-16T14:34:43","slug":"l-glutamine-the-miracle-amino-acid-and-how-you-can-benefit-from-its-use","status":"publish","type":"post","link":"https:\/\/valuecare.wpgamma.com\/index.php\/2025\/09\/16\/l-glutamine-the-miracle-amino-acid-and-how-you-can-benefit-from-its-use\/","title":{"rendered":"L-Glutamine – The Miracle Amino Acid and How You Can Benefit From Its Use"},"content":{"rendered":"
I don\u2019t believe in miracles – I depend upon them. – Raymond Dale<\/strong><\/p>\n
\n

I am absolutely mystified\u2026 For some strange reason\u00a0L-Glutamine<\/a>, as it was officially christened, as of today has not been truly discovered by the world at large! What do I mean by discovered?<\/p>\n

Well, it just seems a little odd to me that an amino acid that composes the greater portion of your skeletal muscle mass and is depleted through daily and excessive physical exertion does not play a bigger role in repair, recovery and general maintenance of\u2026well the greater than 60% of your body.\u00a0L-Glutamine<\/a>\u00a0is an amino acid found in\u00a0Proteins<\/a>\u00a0of all life forms and is classified as a semi-essential or conditionally essential amino acid. This means that under normal circumstances the body can synthesize sufficient\u00a0L-Glutamine<\/a>\u00a0to meet physiological demands. Nonetheless, there are conditions where the body cannot do so.<\/p>\n

So my dilemma is, should I open up the floodgates and exclaim to the world how important glutamine is or should I contribute to the suppression of what I view as one of the most vital elements necessary for bodily integrity and overall health? You know what\u2026 I\u2019m going to do what I do and that is to speak the truth, and I\u2019ll let you determine how vital\u00a0L-Glutamine<\/a>\u00a0is to you. Okay? Great!<\/p>\n

Of late,\u00a0L-Glutamine<\/a>\u00a0has come to be reputed as merely an important amino acid when the body is subjected to such metabolic\u00a0Stress<\/a>\u00a0situations as\u00a0Trauma<\/a>\u00a0(including surgical\u00a0Trauma<\/a>), cancer, sepsis and burns, this list also includes traumas or excessive uses as hard-core training for\u00a0Athletics<\/a>, emotional\u00a0Stress<\/a>\u00a0and the daily rigors of a demanding lifestyle, I couldn\u2019t agree more.<\/p>\n

Under these conditions,\u00a0L-Glutamine<\/a>\u00a0becomes an essential amino acid, and it is therefore very important to ensure adequate intake or replacement of the amino acid in order to meet the increased physiological and psychological demands created by these circumstances. But again, with all the physiological, psychological and shall we even dare say spiritual stressors that we are subjected to\u2026my personal assessment (guess) is that\u00a0L-Glutamine<\/a>\u00a0is far more important to us than those who are in the positions of power, persuasion and leverage might have us believe. Logic dictates that if we fall apart faster, more often and do so frequently\u2026well there is just the system already in place to take care of us\u2026think bout it!<\/p>\n

Luckily\u00a0L-Glutamine<\/a>\u00a0is indeed and without argument the most abundant amino acid found in the body, (thank goodness for science) and plasma (blood)\u00a0L-Glutamine<\/a>\u00a0levels are the highest of any amino acid.\u00a0L-Glutamine<\/a>\u00a0is predominantly manufactured (synthesized) and stored in skeletal muscle. The amino acid L-glutamate is metabolized to\u00a0L-Glutamine<\/a>\u00a0in a reaction catalyzed (To initiate a chemical reaction and enable it to proceed under different conditions) by the enzyme\u00a0L-Glutamine<\/a>\u00a0synthase, a reaction which, in addition to L-glutamate, requires ammonia, ATP and magnesium\u2026ya\u2019 dig?<\/p>\n

And if that isn\u2019t fascinating enough,\u00a0L-Glutamine<\/a>\u00a0is also an overtly multipurpose amino acid and participates in many particular reactions in the body.\u00a0L-Glutamine<\/a>\u00a0is very important in the regulation of acid-base balance and\u00a0L-Glutamine<\/a>\u00a0additionally allows the kidneys to excrete an acid load, protecting the body against acidosis. This is accomplished by the production of ammonia, which binds hydrogen ions, to produce ammonium cations (a positively charged polyatomic ion of the chemical formula NH4+ and a molecular mass of 18.04, resulting from protonation of ammonia (NH3).) that are excreted in the urine along with chloride anions. Bicarbonate ions are simultaneously released into the bloodstream.<\/p>\n

If that just ain\u2019t powerful enough, check this out\u2026glutamine helps protect the body against ammonia toxicity by transporting ammonia, in the form of\u00a0L-Glutamine<\/a>\u2019s amide group, from peripheral tissues to visceral organs, where it can be excreted as ammonium by the kidneys or converted to urea by the liver. Sorry about the science mumbo-jumbo, but because I whole-heartedly feel\u00a0L-Glutamine<\/a>\u00a0is so important, I only think that it is right to convey these messages, so without further delay\u2026a little more uh\u2026mumbo-jumbo (gibberish).<\/p>\n

This miracle amino acid also participates in other metabolic activities such as; serving as the most important nitrogen shuttle, supplying nitrogen for metabolic purposes (from\u00a0L-Glutamine<\/a>-producing tissues, such as skeletal muscle) to\u00a0L-Glutamine<\/a>-consuming tissues. Pretty cool huh? Well that isn\u2019t the whole shebang, please continue.<\/p>\n

Besides all that good stuff,\u00a0L-Glutamine<\/a>\u00a0also participates in the formation of purine and pyrimidine nucleotides, amino sugars (such as\u00a0Glucosamine<\/a>), L-glutamate and other\u00a0Amino Acids<\/a>, nicotinamide adenine dinucleotide and glutathione. As well as the participation in protein synthesis, energy production and, if necessary, the production of D-glucose and glycogen. Importantly,\u00a0L-Glutamine<\/a>\u00a0can serve as the primary respiratory substrate (The material or substance on which an enzyme acts or a surface on which an organism grows or is attached) for the production of energy in enterocytes and lymphocytes.<\/p>\n

Glutamine is considered an immunonutrient, and supplemental\u00a0L-Glutamine<\/a>\u00a0is used in medical foods for such\u00a0Stress<\/a>\u00a0situations as the above mentioned traumas, cancers, infections and burns and post-burn infections to all degrees.<\/p>\n

Supplemental\u00a0L-Glutamine<\/a>\u2019s possible immunomodulatory role may be accounted for in a number of ways.\u00a0L-Glutamine<\/a>\u00a0appears to play a major role in protecting the integrity of the gastrointestinal tract and, in particular, the large intestine. During catabolic states, the integrity of the intestinal mucosa may be compromised with consequent increased intestinal permeability and translocation of Gram-negative bacteria from the large intestine into the body.<\/p>\n

The requirement for\u00a0L-Glutamine<\/a>\u00a0by the intestine, as well as by cells such as lymphocytes, appears to be much greater than that supplied by skeletal muscle, the major storage tissue for\u00a0L-Glutamine<\/a>\u00a0add\u00a0L-Glutamine<\/a>\u00a0is the preferred respiratory fuel for enterocytes, colonocytes and lymphocytes. Therefore, supplying supplemental\u00a0L-Glutamine<\/a>\u00a0under these conditions may do a number of things. For one, it more than likely will reverse the catabolic state by sparing skeletal muscle\u00a0L-Glutamine<\/a>. It also may inhibit translocation of Gram-negative bacteria from the large intestine.\u00a0L-Glutamine<\/a>\u00a0helps maintain secretory IgA, which functions primarily by preventing the attachment of bacteria to mucosal cells.<\/p>\n

Gastrointestinal Performance.<\/strong><\/p>\n

There is now a significant body of evidence that connects\u00a0L-Glutamine<\/a>\u00a0enriched diets with positive intestinal effects; the aiding and maintenance of gut barrier function, intestinal cell propagation, as well as assisting in the general reduction of septic morbidity. The reason for such cleansing properties is thought to emanate from the fact that the intestinal extraction rate of\u00a0L-Glutamine<\/a>\u00a0is higher than that for other\u00a0Amino Acids<\/a>\u00a0and is subsequently thought to be the most viable option when endeavoring to alleviate conditions relating to the intestine.<\/p>\n

These conditions were discovered after comparing plasma concentration within the stomach between\u00a0L-Glutamine<\/a>\u00a0enriched and non\u00a0L-Glutamine<\/a>\u00a0enriched diets. However, even though\u00a0L-Glutamine<\/a>\u00a0is thought to have cleansing properties and effects, it is unknown to what extent it has clinical benefits, due to the varied concentrations of\u00a0L-Glutamine<\/a>\u00a0in varieties of food.<\/p>\n

Moreover,\u00a0L-Glutamine<\/a>\u00a0appears to be required to support the increase of mitogen-stimulated lymphocytes, as well as the production of interleukin-2 (IL-2) and interferon-gamma (IFN-gamma). It is also required for the maintenance of lymphokine-activated killer cells (LAK).\u00a0L-Glutamine<\/a>\u00a0can enhance phagocytosis by neutrophils and monocytes. It can lead to an increased synthesis of glutathione in the intestine, which may also play a role in maintaining the integrity of the intestinal mucosa by ameliorating oxidative\u00a0Stress<\/a>.<\/p>\n

But the precise mechanism of the possible immunomodulatory action of supplemental\u00a0L-Glutamine<\/a>\u00a0on the other hand, still remains unresolved. My guess is and it is more than conceivable that the major effect of\u00a0L-Glutamine<\/a>\u00a0occurs at the level of the intestine (in the tummy). And perchance enteral\u00a0L-Glutamine<\/a>\u00a0acts expressly on intestine-associated lymphoid tissue and stimulates overall\u00a0Immune Function<\/a>\u00a0by that mechanism, without passing beyond the splanchnic bed.<\/p>\n

Glutamine Reduces Post-Burn Infections<\/strong><\/p>\n

By referrence from a fairly recent study in Critical Care Medicine (2003; 31:2444\u20139)\u00a0L-Glutamine<\/a>\u00a0lowers infection risk and may lead to fewer deaths and shorter hospital stays in burn victims. In the study, 41 adults under the age of 65 years with severe burns covering between 20 and 80% of their skin were assigned to receive standard nutrition through a feeding tube supplemented with 4.3 grams of\u00a0L-Glutamine<\/a>\u00a0or supplemented with other\u00a0Amino Acids<\/a>\u00a0(aspartic acid, asparagine, and glycine) every four hours (up to 26 grams per day). Treatment was continued until complete healing of the burns occurred. Time spent in the hospital, incidence of blood infections, and the number of deaths was recorded.<\/p>\n

The incidence of blood infections was three times higher in individuals receiving the control mixture than in those getting supplemental\u00a0L-Glutamine<\/a>\u00a0in their feeding tube. No deaths occurred in the group receiving\u00a0L-Glutamine<\/a>\u00a0among the 19 individuals who survived the first 72 hours, compared with eight deaths among the 16 people in the control group who survived the first 72 hours. Time spent in the hospital was also significantly reduced in those receiving\u00a0L-Glutamine<\/a>. The anticatabolic\/anabolic activity of supplemental\u00a0L-Glutamine<\/a>\u00a0can be explicated by its effect in and its efficiency in sparing skeletal muscle\u00a0L-Glutamine<\/a>\u00a0stores.\u00a0L-Glutamine<\/a>\u00a0powder is a flavorless, easy-mixing, pure, free amino acid powder.<\/p>\n

What it can do for you\u2026<\/strong><\/p>\n

Clinical studies reveal that\u00a0L-Glutamine<\/a>\u00a0supplementation can help support recovery after intensive training by promoting energy replenishment, maintaining a healthy\u00a0Immune System<\/a>\u00a0and by maximizing your body\u2019s buffering capacity against lactic acid build-up.<\/p>\n

Again,\u00a0L-Glutamine<\/a>\u00a0is the most common amino acid found in your muscles – over 6o% of skeletal muscle is indeed\u00a0L-Glutamine<\/a>. It consists of 19% nitrogen, making it the primary transporter of nitrogen into your muscle cells. During extreme training,\u00a0L-Glutamine<\/a>\u00a0levels are greatly depleted in your body, which decreases strength,\u00a0Stamina<\/a>\u00a0and recovery. It could take up to a week for\u00a0L-Glutamine<\/a>\u00a0levels to return to normal.\u00a0L-Glutamine<\/a>\u00a0supplementation can minimize breakdown of muscle and improve protein\u00a0Metabolism<\/a>.<\/p>\n

In addition to playing key roles in protein\u00a0Metabolism<\/a>, cell volumizing and anti-catabolism,\u00a0L-Glutamine<\/a>\u00a0will also increase your ability to secrete Human Growth Hormone, which helps metabolize body-fat and support new muscle tissue growth.\u00a0L-Glutamine<\/a>\u2019s anti-catabolism ability prevents the breakdown of your muscular integrity. This is especially useful for those of you \u2018cutting down\u2019. Especially during the spring into summer when you\u2019re trying to get rid of unwanted body fat, without losing any hard-earned muscle.<\/p>\n

Especially notably because\u00a0L-Glutamine<\/a>\u00a0levels are depleted during workouts, bodybuilders are more susceptible to illnesses and this is why\u00a0L-Glutamine<\/a>\u00a0supplementation is so important, not necessarily to gain more muscle, but for the sustenance of muscular integrity and bodily\u00a0Vitality<\/a>\u00a0and because\u00a0L-Glutamine<\/a>\u00a0supplementation promotes a positive nitrogen balance and prevents the loss of muscle. Recent studies have also shown that taking just 2 grams of\u00a0L-Glutamine<\/a>\u00a0can increase growth hormone levels by a staggering 400%.<\/p>\n

Now, if all this is not proof enough for you to do a little research of your own, then I just don\u2019t know what to tell ya\u2019, but if I have contributed to triggering your interest in\u00a0L-Glutamine<\/a>, I have done what I set out to do\u2026and that is to convey TRUTH! Here is to you, your\u00a0Vitality<\/a>\u00a0and to the truth. \u2013Know Thyself!<\/p>\n

About the author<\/p>\n

Kurt\u2019s website\u00a0http:\/\/www.kreatefitness.com<\/a>, as well as his Provo Utah Private\u00a0Fitness<\/a>\u00a0Facility Synergy\u00a0Fitness<\/a>\u00a0Systems, specializes in in providing leading edge\u00a0Exercise<\/a>\u00a0and nutrition programs and the Neo Physis super premium supplement line. All of these superior products offer superior results.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

I don\u2019t believe in miracles – I depend upon them. – Raymond Dale I am absolutely mystified\u2026 For some strange reason\u00a0L-Glutamine, as it was officially christened, as of today has not been truly discovered by the world at large! What do I mean by discovered? Well, it just seems a little odd to me that […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[56],"tags":[],"class_list":["post-18726","post","type-post","status-publish","format-standard","hentry","category-nutrition"],"_links":{"self":[{"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/posts\/18726","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/comments?post=18726"}],"version-history":[{"count":0,"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/posts\/18726\/revisions"}],"wp:attachment":[{"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/media?parent=18726"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/categories?post=18726"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/valuecare.wpgamma.com\/index.php\/wp-json\/wp\/v2\/tags?post=18726"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}